Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771422 | 0.87 | EP300 (0.49) | POLBKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL9771408 | 0.84 | KMT2A (0.42) | POLBLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL9771377 | 0.82 | ALDH1A1 (0.43) | POLBLMNAKMT2AP2RX4ALDH1A1 | |
| SCHEMBL9771337 | 0.81 | CMA1 (0.50) | LMNAKMT2AALDH1A1MEN1CASP3 | |
| SCHEMBL9826849 | 0.81 | MAPT (0.43) | POLBKMT2AALDH1A1HTTACHE | |
| SCHEMBL9771317 | 0.79 | POLB (0.55) | POLBTRPV6LMNAKMT2AP2RX4 | |
| SCHEMBL9827539 | 0.73 | ALDH1A1 (0.36) | POLBLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL9771335 | 0.71 | ADORA2A (0.48) | POLBLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL9771326 | 0.70 | POLB (0.44) | POLBLMNAKMT2AALDH1A1HTT | |
| SCHEMBL9771316 | 0.67 | ALDH1A1 (0.51) | POLBLMNAALDH1A1HTTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068341-A | OPTICALLY ACTIVE HYDANTOINS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |