Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666580 | 0.87 | ALDH1A1 (0.50) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL7223666 | 0.82 | SMN1; SMN2 (0.41) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL6607470 | 0.82 | CTSB (0.45) | MAOBALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL2821496 | 0.79 | LMNA (0.43) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11227724 | 0.75 | KCNMA1 (0.58) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL11103298 | 0.75 | MEN1 (0.51) | ALDH1A1LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL22587352 | 0.72 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11525238 | 0.72 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29559580 | 0.72 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4942521 | 0.71 | MEN1 (0.48) | MAOBALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226072-B1 | OXIDATION DYE CONTAINING 4-AMINO-2-AMINOMETHYL PHENOL | Wella Aktiengesellschaft (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4797130-A | DYE DEVELOPERS GOOD FOR RED COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| EP-0226072-A1 | Oxidation dye containing 4-amino-2-aminomethyl phenol | Wella Aktiengesellschaft (DE) | 1987-06-24 | — | — | EP | disclosed |