SCHEMBL9827344

SCHEMBL9827344

COc1c(N)c(OC)c(CCO)c(N)c1Cl

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 2/20 0.34
IMPDH1 P20839 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10530293 0.85 KDM4E (0.32) IMPDH2IMPDH1
SCHEMBL9757485 0.82 IMPDH2 (0.35) IMPDH2IMPDH1
SCHEMBL9757345 0.71 IMPDH2 (0.30) IMPDH2IMPDH1
SCHEMBL8432187 0.71 PDE1A (0.36) IMPDH2IMPDH1
SCHEMBL8433353 0.68 PDE1A (0.40)
SCHEMBL10694680 0.67 IMPDH2 (0.33) IMPDH2
SCHEMBL9398192 0.67 CYP1A2 (0.38)
SCHEMBL11866227 0.66 CYP2D6 (0.36) IMPDH2IMPDH1
SCHEMBL11871207 0.66 IMPDH2 (0.33) IMPDH2IMPDH1
SCHEMBL12348441 0.65 GAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0295474-B1 CHLOROMETAPHENYLENEDIAMINES, THEIR USE AS COUPLING AGENTS IN OXYDATION COLOURING OF KERATINIC FIBRES, COLOURITY COMPOSITIONS FOR HAIR CONTAINING THESE COMPOUNDS AND COLOURING PROCESS USING THESE COMPOSITIONS L'OREAL (FR) 1991-07-17 EP disclosed
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 EP disclosed