SCHEMBL10694680

SCHEMBL10694680

COc1c(C)c(N)c(Cl)c(OC)c1N

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20745709 0.75 ALDH1A1 (0.35) IMPDH2
SCHEMBL12348441 0.74 GAA (0.31)
SCHEMBL7627662 0.73 ACHE (0.33) IMPDH2
SCHEMBL10945676 0.72 CA1 (0.33)
SCHEMBL21170586 0.71 IMPDH2 (0.31) IMPDH2
SCHEMBL22927084 0.71 ACHE (0.32)
SCHEMBL10944854 0.70 CA1 (0.32)
SCHEMBL9793464 0.69 ACHE (0.31)
SCHEMBL10947434 0.69 KDM4E (0.32)
SCHEMBL6075100 0.68 ACHE (0.33) IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 EP claimed