Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 6/20 | 0.47 |
| ▸ | FNTB | P49356 | 6/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828282 | 1.00 | BACE1 (0.49) | BACE1FNTAFNTBPGGT1BCASP1 | |
| SCHEMBL9830035 | 0.85 | PSMB5 (0.49) | GRNSORT1CTSLCTSBCTSS | |
| SCHEMBL9830052 | 0.85 | PSMB5 (0.49) | GRNSORT1CTSLCTSBCTSS | |
| SCHEMBL10870329 | 0.83 | REN (0.44) | CTSSMME | |
| SCHEMBL6244616 | 0.82 | CASP1 (0.57) | BACE1FNTAFNTBPGGT1BCASP1 | |
| SCHEMBL6244622 | 0.82 | CASP1 (0.57) | BACE1FNTAFNTBPGGT1BCASP1 | |
| SCHEMBL7317706 | 0.80 | REN (0.52) | — | |
| SCHEMBL7305979 | 0.80 | REN (0.52) | — | |
| SCHEMBL9830000 | 0.80 | CA2 (0.47) | GRNSORT1CTSLMME | |
| SCHEMBL10660207 | 0.80 | CA2 (0.47) | GRNSORT1CTSLCTSSMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |