Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 10/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 9/20 | 0.36 |
| ▸ | PDE2A | O00408 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829076 | 0.83 | LSS (0.36) | PDE3BPDE3AP2RY12PDE2ATP53 | |
| SCHEMBL9829068 | 0.82 | MEN1 (0.33) | TP53MAPT | |
| Hydrochloric Acid SCHEMBL9828345 | 0.81 | PPARG (0.34) | PDE3BPDE3AP2RY12PDE2ATP53 | |
| Oxalic Acid SCHEMBL10674416 | 0.79 | LSS (0.41) | PDE3BPDE3AP2RY12PDE2ATP53 | |
| SCHEMBL9831388 | 0.79 | ALDH1A1 (0.37) | TP53MAPTLSSPPARGCACNA1B | |
| Hydrochloric Acid SCHEMBL9829279 | 0.76 | LSS (0.37) | PDE3BPDE3AP2RY12PDE2ALSS | |
| SCHEMBL9831087 | 0.75 | CNR1 (0.37) | MAPT | |
| SCHEMBL10674566 | 0.70 | LSS (0.40) | PDE3BPDE3AP2RY12PDE2ALSS | |
| SCHEMBL10674795 | 0.70 | LSS (0.40) | PDE3BPDE3AP2RY12PDE2ALSS | |
| SCHEMBL10859447 | 0.70 | MAPT (0.36) | PDE3BPDE3AP2RY12PDE2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |