Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828818 | 0.87 | BCHE (0.41) | PKMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9828953 | 0.84 | CNR1 (0.42) | CNR1GPR55PKMMAPTALDH1A1 | |
| SCHEMBL9829068 | 0.78 | MEN1 (0.33) | PKMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9831579 | 0.77 | NQO2 (0.41) | PKMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9829070 | 0.75 | PDE3B (0.36) | MAPT | |
| SCHEMBL9830460 | 0.74 | CNR1 (0.44) | CNR1GPR55PKMMAPTALDH1A1 | |
| SCHEMBL10669282 | 0.74 | CNR1 (0.44) | CNR1GPR55PKMMAPTALDH1A1 | |
| SCHEMBL9831997 | 0.74 | BCHE (0.44) | PKMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9830507 | 0.73 | NQO2 (0.39) | PKMMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9831187 | 0.73 | CNR1 (0.43) | CNR1GPR55PKMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |