Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9828341 | 0.82 | TP53 (0.31) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL9829070 | 0.82 | PDE3B (0.36) | TP53MAPT | |
| Oxalic Acid SCHEMBL10674415 | 0.82 | HRH3 (0.38) | MEN1KMT2AHRH3L3MBTL1ALDH1A1 | |
| SCHEMBL9831087 | 0.78 | CNR1 (0.37) | MEN1KMT2AMAPTLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9829276 | 0.76 | ALDH1A1 (0.35) | MEN1KMT2AMAPTLMNAHRH3 | |
| SCHEMBL9831579 | 0.72 | NQO2 (0.41) | MEN1KMT2ATP53MAPTLMNA | |
| Hydrochloric Acid SCHEMBL9828762 | 0.70 | MEN1 (0.33) | MEN1KMT2ATP53MAPTLMNA | |
| SCHEMBL9829867 | 0.69 | NQO2 (0.36) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| Oxalic Acid SCHEMBL9831201 | 0.69 | DRD2 (0.35) | MEN1KMT2ATP53MAPTALDH1A1 | |
| SCHEMBL9830047 | 0.68 | SCN9A (0.34) | MEN1KMT2AMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |