Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702052 | 0.86 | NPC1 (0.43) | NQO1PPARANPC1LMNATDP1 | |
| SCHEMBL7362624 | 0.84 | NQO1 (0.40) | NQO1PPARATDP1MEN1KMT2A | |
| SCHEMBL12261462 | 0.82 | MAPT (0.47) | NQO1PPARATDP1MEN1MAPT | |
| SCHEMBL2769199 | 0.80 | MAPT (0.49) | NPC1LMNAMEN1MAPTALOX12 | |
| SCHEMBL9237800 | 0.79 | FFAR1 (0.48) | NQO1LMNATDP1MEN1MAPT | |
| SCHEMBL9633680 | 0.79 | LTA4H (0.53) | NQO1PPARALMNAMEN1KMT2A | |
| SCHEMBL12269248 | 0.78 | LMNA (0.57) | NPC1LMNAMAPK1 | |
| SCHEMBL3720666 | 0.77 | NQO1 (0.67) | NQO1LMNATDP1MAPTKDM4E | |
| SCHEMBL10695387 | 0.77 | LMNA (0.54) | PPARALMNAMAPTPPARGPPARD | |
| SCHEMBL6272310 | 0.77 | LMNA (0.37) | LMNATDP1MEN1MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199281-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND INSECTICIDAL, ACARICIDAL, NEMATICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4837217-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-06 | — | — | US | disclosed |