Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 5/20 | 0.47 |
| ▸ | ACE | P12821 | 5/20 | 0.47 |
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719401 | 0.86 | ACE (0.57) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL3719400 | 0.86 | ACE (0.57) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL28068999 | 0.84 | L3MBTL1 (0.56) | POLBFOLH1L3MBTL1CTSLCTSS | |
| SCHEMBL18837326 | 0.83 | ITGB1 (0.53) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL16423 | 0.83 | ACE (0.65) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL13536744 | 0.83 | CTSK (0.62) | ITGB3ITGAVITGA2BPOLBCTSL | |
| SCHEMBL268723 | 0.83 | ACE (0.65) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL268722 | 0.83 | ACE (0.65) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL29907894 | 0.83 | ACE (0.65) | ITGB3ITGB1ITGAVITGA2BITGB5 | |
| SCHEMBL9828630 | 0.82 | TACR1 (0.58) | ITGB1POLBFOLH1L3MBTL1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |