Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828889 | 1.00 | MAPK1 (0.44) | MAPK1ITGB3ITGA2BITGAVALDH1A1 | |
| SCHEMBL9828822 | 0.98 | MAPK1 (0.45) | MAPK1ITGB3ITGA2BITGAVALDH1A1 | |
| SCHEMBL9828841 | 0.98 | MAPK1 (0.45) | MAPK1ITGB3ITGA2BITGAVALDH1A1 | |
| Water SCHEMBL11367778 | 0.97 | MAPK1 (0.44) | MAPK1ITGB3ITGA2BALDH1A1CYP3A4 | |
| SCHEMBL11338769 | 0.90 | MAPK1 (0.46) | MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL11331027 | 0.88 | CTSL (0.43) | MAPK1ALDH1A1CYP3A4 | |
| SCHEMBL2177818 | 0.88 | BMP1 (0.48) | ITGB3ITGA2BITGAVFOLH1 | |
| SCHEMBL28011820 | 0.88 | BMP1 (0.48) | ITGB3ITGA2BITGAVFOLH1 | |
| SCHEMBL24795018 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BITGAVMMEECE1 | |
| SCHEMBL254638 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BITGAVMMEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |