Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.45 |
| ▸ | GART | P22102 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828944 | 1.00 | CA2 (0.52) | CA2PLK1TRPV1CA1CA12 | |
| SCHEMBL9831590 | 0.83 | CA2 (0.53) | CA2CA1CA12CA9L3MBTL1 | |
| SCHEMBL9831597 | 0.83 | CA2 (0.53) | CA2CA1CA12CA9L3MBTL1 | |
| SCHEMBL9831247 | 0.83 | CA2 (0.53) | CA2CA1CA12CA9L3MBTL1 | |
| SCHEMBL9831250 | 0.83 | CA2 (0.53) | CA2CA1CA12CA9L3MBTL1 | |
| SCHEMBL4955422 | 0.83 | ALDH1A1 (0.53) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL9830017 | 0.83 | ALDH1A1 (0.53) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL9829504 | 0.82 | CA2 (0.55) | CA2CA1CA12CA9L3MBTL1 | |
| SCHEMBL9829499 | 0.82 | CA2 (0.55) | CA2CA1CA12CA9L3MBTL1 | |
| SCHEMBL9829328 | 0.80 | MAPT (0.69) | CA2PLK1TRPV1CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |