Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442800 | 0.89 | MEN1 (0.58) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10968990 | 0.83 | LMNA (0.54) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL7854884 | 0.83 | MAPT (0.54) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL417015 | 0.83 | ALOX5 (0.58) | MEN1KMT2A | |
| SCHEMBL10574439 | 0.79 | L3MBTL1 (0.59) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL11464005 | 0.78 | CYP3A4 (0.62) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28472108 | 0.78 | MEN1 (0.49) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11464001 | 0.77 | TSHR (0.54) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL27588745 | 0.77 | MEN1 (0.62) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL875812 | 0.75 | MEN1 (1.00) | MAPTMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227055-B1 | INSECTICIDAL PYRAZOLINES | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-08-07 | — | — | EP | disclosed |
| US-4888340-A | Insecticides pyrazolines, compositions and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-12-19 | — | — | US | disclosed |
| EP-0227055-A1 | Insecticidal pyrazolines | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-07-01 | — | — | EP | disclosed |
| EP-0058424-B1 | PYRAZOLINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
| EP-0058424-A2 | Pyrazoline derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-08-25 | — | — | EP | disclosed |