SCHEMBL417015

SCHEMBL417015

O=C(c1ccc(O)cc1Cc1ccccc1)c1ccc(O)cc1Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.58
MEN1 O00255 1/20 0.51
USP2 O75604 1/20 0.51
GAA P10253 1/20 0.51
KMT2A Q03164 1/20 0.51
KEAP1 Q14145 1/20 0.51
NFE2L2 Q16236 1/20 0.51
PTPN1 P18031 3/20 0.50
BCL2 P10415 2/20 0.50
BCL2L1 Q07817 1/20 0.50
PTPN2 P17706 1/20 0.50
PTPN6 P29350 1/20 0.50
HSD17B3 P37058 1/20 0.48
HNF4A P41235 1/20 0.45
PDK1 Q15118 1/20 0.44
MPO P05164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27588745 0.93 MEN1 (0.62) ALOX5MEN1USP2GAAKMT2A
SCHEMBL310681 0.89 PTPN1 (0.58) ALOX5MEN1USP2GAAKMT2A
Zinc Ion SCHEMBL11175319 0.85 ALOX5 (0.53) ALOX5MEN1USP2GAAKMT2A
SCHEMBL2519910 0.85 ALOX5 (0.53) ALOX5MEN1USP2GAAKMT2A
SCHEMBL28048457 0.83 HSP90AB1 (0.56) ALOX5MEN1USP2GAAKMT2A
SCHEMBL10968990 0.83 LMNA (0.54) ALOX5MEN1KMT2APDK1
SCHEMBL7854884 0.83 MAPT (0.54) ALOX5MEN1GAAKMT2A
SCHEMBL9828997 0.83 MAPT (0.60) MEN1KMT2A
(Chloromethyl)Benzene SCHEMBL7198605 0.82 PTPN1 (0.51) ALOX5MEN1USP2GAAKMT2A
SCHEMBL6762297 0.82 TDP1 (0.58) ALOX5KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1699840-B1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-22 EP claimed
US-20120022177-A1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2012-01-26 US claimed
JP-4791375-B2 2011-10-12 JP claimed
US-20070238795-A1 Non-Fugitive Catalysts Containing Imine Linkages and Tertiary Amines, and Polyurethane Products made Therefrom DOW GLOBAL TECHNOLOGIES LLC 2007-10-11 US claimed
EP-1699840-A1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM Dow Gloval Technologies Inc. (US) 2006-09-13 EP claimed
WO-2005063840-A1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2005-07-14 WO claimed
CN-114502659-A Resin composition, resin sheet, cured film, method for producing cured film, semiconductor device, organic EL display device, and display device 东丽株式会社 2022-05-13 CN disclosed
US-20170340955-A1 THERMALLY IMAGEABLE SUBSTRATE WITH ENCAPSULATED COREACTANT APPVION OPERATIONS, INC. 2017-11-30 US disclosed
US-20160096105-A1 Direct Thermal Variable Printing Substrate APPVION, INC. (US) 2016-04-07 US disclosed
EP-1699840-B1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-22 EP disclosed
US-20120022177-A1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2012-01-26 US disclosed
WO-2009078904-A1 HEAT-SENSITIVE RECORD MATERIAL APPLETON PAPERS INC. (US) 2009-06-25 WO disclosed
US-20090155613-A1 Heat-Sensitive record material APPLETON PAPERS INC. (US) 2009-06-18 US disclosed
WO-2002100813-A2 MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ELI LILLY AND COMPANY (US) 2002-12-19 WO disclosed
EP-0517380-B1 Thermally-reponsive record material APPLETON PAPER INC (US) 1997-08-27 EP disclosed
EP-0517380-A1 Thermally-reponsive record material APPLETON PAPERS INC. (US) 1992-12-09 EP disclosed
US-5164357-A THERMALLY-RESPONSIVE RECORD MATERIAL APPLETON PAPERS INC. (US) 1992-11-17 US disclosed
EP-0058424-B1 PYRAZOLINE DERIVATIVES NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1985-09-18 EP disclosed
US-4540706-A Insecticidal 1-N-phenylcarbamoyl-3-(4-difluoromethoxyphenyl)-4-phenyl-2-pyrazoline derivatives NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1985-09-10 US disclosed
EP-0058424-A2 Pyrazoline derivatives NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1982-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238795-A1 Non-Fugitive Catalysts Containing Imine Linkages and Tertiary Amines, and Polyurethane Products made Therefrom UFM1, INMT, PUF60 ALOX5 834/4885MEN1 2600/4885USP2 843/4885
US-20120022177-A1 NON-FUGITIVE CATALYSTS CONTAINING IMINE LINKAGES AND TERTIARY AMINES, AND POLYURETHANE PRODUCTS MADE THEREFROM UFM1, INMT, PUF60 ALOX5 834/4885MEN1 2600/4885USP2 843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.