Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829914 | 0.87 | HSD17B2 (0.51) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9829790 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9831170 | 0.82 | KMT2A (0.59) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9829764 | 0.78 | MEN1 (0.45) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9830967 | 0.78 | SRD5A1 (0.49) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9831086 | 0.74 | POLB (0.44) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL16335558 | 0.72 | MAPT (0.57) | ALDH1A1MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL9832862 | 0.72 | ALDH1A1 (0.52) | ALDH1A1RAB9ACA12CA1CA2 | |
| SCHEMBL17033980 | 0.71 | CA1 (0.56) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL10944876 | 0.71 | CA12 (0.56) | ALDH1A1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | disclosed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | disclosed |