Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9829279 | 0.97 | LSS (0.37) | ALDH1A1CACNA1BCACNA1HKMT2AMEN1 | |
| SCHEMBL9830032 | 0.89 | CACNA1B (0.43) | ALDH1A1CACNA1BCACNA1HKMT2AMEN1 | |
| SCHEMBL9830080 | 0.87 | ALDH1A1 (0.42) | ALDH1A1CACNA1BCACNA1HKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9829638 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CACNA1BCACNA1HKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9828345 | 0.82 | PPARG (0.34) | ALDH1A1CACNA1BCACNA1HKMT2AMEN1 | |
| SCHEMBL9829076 | 0.81 | LSS (0.36) | CACNA1BCACNA1HPPARGLSSMAPT | |
| Hydrochloric Acid SCHEMBL9829276 | 0.81 | ALDH1A1 (0.35) | ALDH1A1CACNA1BCACNA1HKMT2AMEN1 | |
| SCHEMBL9830856 | 0.80 | TMEM97 (0.50) | KMT2AMEN1HRH3KDM4EOPRM1 | |
| SCHEMBL9829460 | 0.79 | MAPT (0.38) | ALDH1A1KMT2AMEN1HRH3KDM4E | |
| SCHEMBL9829070 | 0.79 | PDE3B (0.36) | CACNA1BCACNA1HPPARGLSSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |