Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829868 | 1.00 | SLC6A9 (0.45) | SLC6A9ITGB3ITGA2BPOLBKMT2A | |
| SCHEMBL9829783 | 0.92 | ITGB3 (0.49) | ITGB3ITGA2BKMT2ACTSLCTSB | |
| SCHEMBL9829792 | 0.92 | ITGB3 (0.49) | ITGB3ITGA2BKMT2ACTSLCTSB | |
| SCHEMBL9828875 | 0.86 | MAPK1 (0.44) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL9828889 | 0.86 | MAPK1 (0.44) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL9828822 | 0.86 | MAPK1 (0.45) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL9828841 | 0.86 | MAPK1 (0.45) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL9829443 | 0.85 | GPR139 (0.45) | SLC6A9KMT2AMEN1ACE | |
| SCHEMBL9829425 | 0.85 | GPR139 (0.45) | SLC6A9KMT2AMEN1ACE | |
| SCHEMBL9829179 | 0.85 | GPR139 (0.47) | SLC6A9KMT2AMEN1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |