Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830032 | 0.97 | CACNA1B (0.43) | ALDH1A1KDM4ECACNA1BCACNA1HLSS | |
| Hydrochloric Acid SCHEMBL9829638 | 0.93 | ALDH1A1 (0.41) | ALDH1A1KDM4ECACNA1BCACNA1HLSS | |
| Hydrochloric Acid SCHEMBL9829279 | 0.89 | LSS (0.37) | ALDH1A1KDM4ECACNA1BCACNA1HLSS | |
| SCHEMBL9831388 | 0.87 | ALDH1A1 (0.37) | ALDH1A1KDM4ECACNA1BCACNA1HLSS | |
| Hydrochloric Acid SCHEMBL9829276 | 0.86 | ALDH1A1 (0.35) | ALDH1A1KDM4ECACNA1BCACNA1HLSS | |
| SCHEMBL9828934 | 0.85 | SMPD1 (0.49) | KDM4ECYP2C19TP53CYP1A2CYP2D6 | |
| Oxalic Acid SCHEMBL10669220 | 0.85 | KDM4E (0.48) | ALDH1A1KDM4ESMN1; SMN2CYP2C19SLC22A1 | |
| SCHEMBL9829983 | 0.85 | CYP1A2 (0.40) | ALDH1A1KDM4ESMN1; SMN2BCHECYP2C19 | |
| Hydrochloric Acid SCHEMBL9829648 | 0.84 | BCHE (0.39) | ALDH1A1KDM4EBCHEACHEMEN1 | |
| SCHEMBL9830856 | 0.83 | TMEM97 (0.50) | KDM4EBCHEACHESLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |