Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830032 | 0.84 | CACNA1B (0.43) | SIGMAR1HRH3SLC6A2SLC6A4KDM4E | |
| SCHEMBL9830080 | 0.83 | ALDH1A1 (0.42) | SIGMAR1SLC6A2SLC6A4ACHEBCHE | |
| SCHEMBL9832244 | 0.82 | HRH3 (0.42) | HRH3MAOB | |
| SCHEMBL9831388 | 0.80 | ALDH1A1 (0.37) | HRH3KDM4EMEN1KMT2AOPRM1 | |
| Hydrochloric Acid SCHEMBL9829638 | 0.79 | ALDH1A1 (0.41) | SIGMAR1SLC6A2SLC6A4ACHEBCHE | |
| Hydrochloric Acid SCHEMBL9829279 | 0.79 | LSS (0.37) | KDM4EMEN1KMT2AOPRM1 | |
| Oxalic Acid SCHEMBL10669220 | 0.76 | KDM4E (0.48) | KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9829276 | 0.74 | ALDH1A1 (0.35) | HRH3KDM4EMEN1KMT2A | |
| SCHEMBL9829983 | 0.74 | CYP1A2 (0.40) | SIGMAR1SLC6A2SLC6A4BCHEKDM4E | |
| SCHEMBL9828934 | 0.73 | SMPD1 (0.49) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |