Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830987 | 0.90 | GAA (0.54) | MAPTSMN1; SMN2KMT2AKDM4ERAB9A | |
| SCHEMBL9829467 | 0.89 | ROCK1 (0.42) | PPARAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL9832642 | 0.88 | SMN1; SMN2 (0.64) | PPARAMAPTSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9830803 | 0.87 | ALDH1A1 (0.62) | MAPTSMN1; SMN2KMT2ARAB9ANPC1 | |
| SCHEMBL9832312 | 0.87 | ROCK1 (0.51) | MAPTSMN1; SMN2KMT2AKDM4ERAB9A | |
| SCHEMBL9823493 | 0.86 | KDM4E (0.46) | MAPTSMN1; SMN2KMT2AKDM4ERAB9A | |
| SCHEMBL9832252 | 0.84 | MAPT (0.43) | MAPTSMN1; SMN2KMT2AKDM4EPOLB | |
| SCHEMBL9830151 | 0.81 | MAPT (0.46) | PPARAMAPTSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9823479 | 0.80 | TLR7 (0.61) | MAPTSMN1; SMN2KMT2AKDM4ERAB9A | |
| SCHEMBL9830334 | 0.76 | RAB9A (0.48) | MAPTSMN1; SMN2KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |