Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.57 |
| ▸ | F2R | P25116 | 1/20 | 0.55 |
| ▸ | CCR5 | P51681 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138087 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2RECQLLMNAITGB3ITGA2B | |
| SCHEMBL4696189 | 0.97 | SMN1; SMN2 (0.67) | SMN1; SMN2RECQLLMNAITGB3ITGA2B | |
| SCHEMBL4696193 | 0.97 | SMN1; SMN2 (0.67) | SMN1; SMN2RECQLLMNAITGB3ITGA2B | |
| Formic Acid SCHEMBL27557118 | 0.94 | SMN1; SMN2 (0.58) | SMN1; SMN2RECQLLMNAITGB3ITGA2B | |
| SCHEMBL9829153 | 0.94 | ITGB3 (0.59) | SMN1; SMN2RECQLLMNAITGB3ITGA2B | |
| SCHEMBL4130312 | 0.88 | RECQL (0.62) | SMN1; SMN2RECQLLMNACCR5KCNH2 | |
| SCHEMBL1573959 | 0.86 | RECQL (0.59) | SMN1; SMN2RECQLLMNAITGB3ITGA2B | |
| SCHEMBL1573757 | 0.86 | RECQL (0.59) | SMN1; SMN2RECQLLMNAITGB3ITGA2B | |
| SCHEMBL5424938 | 0.85 | LMNA (0.61) | SMN1; SMN2RECQLLMNACCR5KCNH2 | |
| SCHEMBL7113507 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2RECQLLMNAITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |