Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830300 | 0.94 | CPB2 (0.42) | GSRRNPEPCPB2SLC6A5CYP2D6 | |
| SCHEMBL9831408 | 0.89 | SLC6A5 (0.49) | GSRRNPEPSLC6A5GNAI3GNAO1 | |
| SCHEMBL9827876 | 0.89 | SLC6A5 (0.46) | GSRRNPEPCPB2SLC6A5GNAI3 | |
| SCHEMBL179793 | 0.87 | SLC6A5 (0.51) | SLC6A5GNAI3GNAO1GNAI1GPR84 | |
| SCHEMBL9034495 | 0.87 | SLC6A5 (0.51) | SLC6A5GNAI3GNAO1GNAI1GPR84 | |
| SCHEMBL9719716 | 0.87 | SLC6A5 (0.51) | SLC6A5GNAI3GNAO1GNAI1GPR84 | |
| SCHEMBL8936404 | 0.87 | SLC6A5 (0.51) | SLC6A5GNAI3GNAO1GNAI1GPR84 | |
| SCHEMBL7500371 | 0.86 | GABRR1 (0.46) | GSRRNPEPSLC6A3GPR84 | |
| SCHEMBL9349434 | 0.86 | GPR84 (0.52) | GPR84FFAR1 | |
| SCHEMBL9829184 | 0.85 | CPB2 (0.41) | GSRRNPEPCPB2SLC6A5GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |