Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 7/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156731 | 0.90 | CASP1 (0.60) | CASP1ATMCTSLCTSS | |
| SCHEMBL6955527 | 0.90 | CASP1 (0.60) | CASP1ATMCTSLCTSS | |
| SCHEMBL6156740 | 0.90 | CASP1 (0.60) | CASP1ATMCTSLCTSS | |
| SCHEMBL3857870 | 0.86 | CASP1 (0.51) | CASP1 | |
| SCHEMBL14562401 | 0.84 | KLK1 (0.57) | CASP1 | |
| SCHEMBL5700951 | 0.84 | F2 (0.49) | F2PLAUPLATCASP1ATM | |
| SCHEMBL5700948 | 0.84 | F2 (0.49) | F2PLAUPLATCASP1ATM | |
| SCHEMBL10885697 | 0.82 | CTRB1 (0.51) | CASP1ATMCTSLCTSS | |
| SCHEMBL1232637 | 0.82 | CASP1 (0.51) | CASP1ATMCTSLCTSS | |
| SCHEMBL15654961 | 0.82 | CASP1 (0.51) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |