Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700948 | 1.00 | F2 (0.49) | F2PLAUPLATMEN1LMNA | |
| SCHEMBL16201457 | 0.91 | ATM (0.54) | MEN1LMNAKMT2AATMCYP2C9 | |
| SCHEMBL6958944 | 0.91 | ATM (0.54) | MEN1LMNAKMT2AATMCYP2C9 | |
| SCHEMBL6650427 | 0.87 | PPARG (0.47) | ABCB1ATMCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4635039 | 0.84 | CTSK (0.49) | ATMCTSLCTSS | |
| SCHEMBL9830798 | 0.84 | F2 (0.52) | F2PLAUPLATATMCASP1 | |
| SCHEMBL16970673 | 0.83 | OPRK1 (0.43) | F2PLAUPLATABCB1ATM | |
| SCHEMBL3571107 | 0.83 | CA1 (0.51) | ATMCYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL1825255 | 0.81 | P2RX7 (0.47) | ATMCASP1 | |
| SCHEMBL6135483 | 0.81 | CASP1 (0.54) | MEN1LMNAKMT2AATMCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |