Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830821 | 1.00 | LMNA (0.45) | LMNAALDH1A1SMN1; SMN2GAACXCR2 | |
| SCHEMBL10440896 | 0.92 | POLB (0.48) | LMNAALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL9828908 | 0.88 | KDM4E (0.51) | LMNAALDH1A1SMN1; SMN2GAACXCR2 | |
| SCHEMBL9828915 | 0.88 | KDM4E (0.51) | LMNAALDH1A1SMN1; SMN2GAACXCR2 | |
| SCHEMBL193093 | 0.84 | KCNN4 (0.44) | LMNAALDH1A1SMN1; SMN2GAACXCR2 | |
| SCHEMBL5711399 | 0.84 | MEN1 (0.51) | LMNAALDH1A1SMN1; SMN2CXCR2POLB | |
| SCHEMBL31329451 | 0.83 | CXCR2 (0.39) | ALDH1A1GAACXCR2KDM4EHPGD | |
| SCHEMBL7319974 | 0.81 | CA12 (0.43) | GAACXCR2RAB9ANPC1MEN1 | |
| SCHEMBL27158981 | 0.81 | CA12 (0.43) | GAACXCR2RAB9ANPC1MEN1 | |
| SCHEMBL9829583 | 0.78 | CXCR2 (0.42) | LMNAALDH1A1CXCR2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |