Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911340 | 0.86 | REN (0.47) | RENALDH1A1MAPTRECQLCYP1A2 | |
| SCHEMBL15337549 | 0.85 | REN (0.53) | RENALDH1A1MAPTRECQLCYP1A2 | |
| SCHEMBL13091047 | 0.84 | ALDH1A1 (0.47) | RENALDH1A1MAPTRECQLCYP1A2 | |
| SCHEMBL1911119 | 0.83 | REN (0.45) | RENALDH1A1MAPTRECQLCYP1A2 | |
| SCHEMBL89400 | 0.83 | REN (0.62) | RENALDH1A1MAPTRECQLCYP1A2 | |
| SCHEMBL14320708 | 0.81 | PDE3B (0.51) | RENALDH1A1MAPTRECQLCYP19A1 | |
| SCHEMBL9830281 | 0.79 | ALDH1A1 (0.43) | RENALDH1A1MAPTRECQLCYP1A2 | |
| SCHEMBL17434442 | 0.77 | ATAD2 (0.44) | RENALDH1A1MAPTRECQLCYP1A2 | |
| SCHEMBL8039164 | 0.77 | ALDH1A1 (0.60) | ALDH1A1MAPTRECQLCYP1A2CYP2C9 | |
| SCHEMBL16601598 | 0.76 | ALDH1A1 (0.40) | RENALDH1A1MAPTRECQLUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255601-B1 | DIALKYLNALEINIMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDE | NIHON BAYER AGROCHEM K.K. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4729784-A | 1-(1,4-benzoxazin-3-on-6-yl)-dialkylmaleimides and use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-03-08 | — | — | US | disclosed |
| EP-0255601-A2 | Dialkylnaleinimides, process for their preparation and their use as herbicide | NIHON BAYER AGROCHEM K.K. (JP) | 1988-02-10 | — | — | EP | disclosed |