Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830965 | 1.00 | CTSB (0.48) | CTSBGPR139HPGDPLK1ALDH1A1 | |
| SCHEMBL9829668 | 0.92 | GPR139 (0.49) | GPR139HPGDPLK1ALDH1A1MEN1 | |
| SCHEMBL9829673 | 0.92 | GPR139 (0.49) | GPR139HPGDPLK1ALDH1A1MEN1 | |
| SCHEMBL9828116 | 0.87 | PLK1 (0.50) | CTSBHPGDPLK1ALDH1A1HDAC8 | |
| SCHEMBL9828124 | 0.87 | PLK1 (0.50) | CTSBHPGDPLK1ALDH1A1HDAC8 | |
| SCHEMBL9831837 | 0.82 | GPR139 (0.59) | GPR139ALDH1A1MEN1KMT2AMME | |
| SCHEMBL9831842 | 0.82 | GPR139 (0.59) | GPR139ALDH1A1MEN1KMT2AMME | |
| SCHEMBL25388151 | 0.80 | PLK1 (0.57) | HPGDPLK1ALDH1A1MEN1KMT2A | |
| SCHEMBL735538 | 0.80 | PLK1 (0.57) | HPGDPLK1ALDH1A1MEN1KMT2A | |
| SCHEMBL25386182 | 0.80 | PLK1 (0.57) | HPGDPLK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |