Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830397 | 0.87 | HTR2B (0.45) | ALDH1A1NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL9832086 | 0.85 | KDM4E (0.48) | ALDH1A1NPC1LMNARAB9ACDK5 | |
| SCHEMBL9832310 | 0.85 | MAPT (0.40) | ALDH1A1NPC1LMNARAB9ACDK5 | |
| SCHEMBL9830880 | 0.84 | CDK5 (0.52) | ALDH1A1NPC1LMNARAB9ACDK5 | |
| SCHEMBL9829826 | 0.82 | RAB9A (0.49) | ALDH1A1NPC1LMNARAB9ACDK5 | |
| SCHEMBL9833230 | 0.82 | DDX3X (0.47) | NPC1RAB9A | |
| SCHEMBL9830487 | 0.81 | RAB9A (0.48) | ALDH1A1NPC1LMNARAB9ACDK5 | |
| SCHEMBL9829998 | 0.81 | GRM5 (0.44) | ALDH1A1NPC1LMNARAB9AGRM5 | |
| SCHEMBL9832511 | 0.81 | CDK5 (0.55) | ALDH1A1NPC1RAB9ACDK5CDK5R1 | |
| SCHEMBL9831082 | 0.80 | CCNA2 (0.49) | ALDH1A1NPC1LMNARAB9ACDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |