Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831314 | 0.85 | ALDH1A1 (0.40) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9830272 | 0.84 | SGMS2 (0.43) | GAACCNA2CDK2CCNA1CDK5 | |
| SCHEMBL9830397 | 0.84 | HTR2B (0.45) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL9830897 | 0.83 | MAPT (0.56) | KDM4ENPC1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9832310 | 0.82 | MAPT (0.40) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9831306 | 0.81 | MAPT (0.49) | RAB9ASMN1; SMN2ALDH1A1HPGDTP53 | |
| SCHEMBL9830880 | 0.81 | CDK5 (0.52) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9831158 | 0.81 | CDC25A (0.49) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9830869 | 0.80 | ROCK1 (0.54) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 | |
| SCHEMBL9823416 | 0.79 | IRAK4 (0.51) | KDM4ERAB9ANPC1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |