Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831314 | 0.87 | ALDH1A1 (0.40) | CDK5CDK5R1RAB9ASMN1; SMN2CCNA2 | |
| SCHEMBL9832310 | 0.86 | MAPT (0.40) | CDK5CDK5R1RAB9ASMN1; SMN2CCNA2 | |
| SCHEMBL9830880 | 0.85 | CDK5 (0.52) | CDK5CDK5R1RAB9ASMN1; SMN2CCNA2 | |
| SCHEMBL9832086 | 0.84 | KDM4E (0.48) | CDK5CDK5R1RAB9ASMN1; SMN2CCNA2 | |
| SCHEMBL9833230 | 0.83 | DDX3X (0.47) | RAB9ANPC1GAA | |
| SCHEMBL9831082 | 0.81 | CCNA2 (0.49) | CDK5CDK5R1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL9830272 | 0.80 | SGMS2 (0.43) | CDK5CDK5R1CCNA2CDK2CCNA1 | |
| SCHEMBL9831310 | 0.79 | RAB9A (0.40) | CDK5CDK5R1RAB9ACASP3SMN1; SMN2 | |
| SCHEMBL9829838 | 0.79 | RAB9A (0.49) | CDK5CDK5R1RAB9ASMN1; SMN2CCNA2 | |
| SCHEMBL9829473 | 0.79 | KDM4E (0.42) | RAB9ASMN1; SMN2MAPTPIM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |