Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661171 | 0.81 | TOP1 (0.57) | KCNMA1MAPTGAAALDH1A1TDP1 | |
| SCHEMBL4319185 | 0.81 | SNCA (0.65) | SNCANR1H4MAPTGAAALDH1A1 | |
| SCHEMBL18360223 | 0.80 | HDAC1 (0.57) | HDAC1KCNMA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL8777865 | 0.79 | HDAC1 (0.58) | HDAC1TOP1TOP2ATOP2BMAPK1 | |
| SCHEMBL2605585 | 0.79 | HDAC1 (0.70) | HDAC1SNCAKCNMA1MAPTCYP1A2 | |
| SCHEMBL7129217 | 0.78 | PTGS1 (0.57) | SNCANR1H4MAPTGAAALDH1A1 | |
| SCHEMBL2605584 | 0.76 | HDAC1 (0.68) | HDAC1KCNMA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL19986271 | 0.76 | HDAC1 (0.52) | HDAC1KCNMA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL14088959 | 0.75 | HDAC1 (0.74) | HDAC1KCNMA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL29999394 | 0.75 | MEN1 (0.56) | HDAC1SNCAKCNMA1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283035-B1 | BENZOXAZOLE DERIVATIVES AND PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |
| US-4948900-A | INTERMEDIATES FOR DIABETES THERAPEUTIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4897393-A | ANTIDIABETIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0283035-A1 | Benzoxazole derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |