SCHEMBL19986271

SCHEMBL19986271

CC(c1ccc(C(=O)Nc2cc(N)ccc2O)cc1)(c1ccc(C(=O)Nc2cc(N)ccc2O)cc1)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 3/20 0.52
KCNMA1 Q12791 4/20 0.49
AKT1 P31749 1/20 0.46
PTGS1 P23219 7/20 0.46
MAPT P10636 3/20 0.45
GAA P10253 1/20 0.45
MAPK1 P28482 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
HDAC2 Q92769 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600606 0.92 HDAC1 (0.55) HDAC1KCNMA1AKT1PTGS1MAPT
SCHEMBL14502927 0.86 HDAC1 (0.54) HDAC1KCNMA1AKT1PTGS1MAPT
SCHEMBL18360223 0.86 HDAC1 (0.57) HDAC1KCNMA1PTGS1MAPTGAA
SCHEMBL12937567 0.85 KCNMA1 (0.68) HDAC1KCNMA1AKT1MAPTGAA
SCHEMBL12151323 0.85 HDAC1 (0.58) HDAC1KCNMA1AKT1PTGS1MAPT
SCHEMBL2605585 0.83 HDAC1 (0.70) HDAC1KCNMA1MAPTGAAMAPK1
SCHEMBL19846834 0.83 KCNMA1 (0.60) HDAC1KCNMA1AKT1MAPTGAA
SCHEMBL10069697 0.81 HDAC1 (0.58) HDAC1KCNMA1AKT1PTGS1MAPT
SCHEMBL30713470 0.81 PTGS1 (0.59) HDAC1KCNMA1PTGS1MAPTGAA
SCHEMBL29167830 0.81 PTGS1 (0.59) HDAC1KCNMA1PTGS1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11860538-B2 Photosensitive resin composition, heterocyclic ring-containing polymer precursor, cured film, laminate, method for producing cured film, and semiconductor device FUJIFILM CORPORATION (JP) 2024-01-02 US disclosed
US-11802181-B2 Di-amine compound, and heat-resistant resin and resin composition using the same TORAY INDUSTRIES, INC. (JP) 2023-10-31 US disclosed
US-20230141241-A1 SCINTILLATOR PANEL AND SCINTILLATOR PANEL MANUFACTURING METHOD TORAY INDUSTRIES, INC. (JP) 2023-05-11 US disclosed
US-20180222164-A1 LAMINATE, METHOD FOR MANUFACTURING LAMINATE, SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING THE SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-08-09 US disclosed
US-20180215874-A1 RESIN, COMPOSITION, CURED FILM, METHOD FOR MANUFACTURING CURED FILM AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-08-02 US disclosed
US-20180118887-A1 PRECURSOR COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING PRECURSOR COMPOSITION, CURED FILM, METHOD FOR PRODUCING CURED FILM, AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed
US-20180118887-A1 PRECURSOR COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING PRECURSOR COMPOSITION, CURED FILM, METHOD FOR PRODUCING CURED FILM, AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed
US-20180079864-A1 POLYIMIDE PRECURSOR COMPOSITION, PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, METHOD FOR PRODUCING CURED FILM, A SEMICONDUCTOR DEVICE, AND METHOD FOR PRODUCING POLYIMIDE PRECURSOR COMPOSITION FUJIFILM CORPORATION (JP) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11802181-B2 Di-amine compound, and heat-resistant resin and resin composition using the same CAD, ARID2, SMC3 HDAC1 1226/4885KCNMA1 2594/4885AKT1 3280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.