Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830695 | 0.82 | MAOB (0.32) | KCNQ2MEN1KMT2A | |
| SCHEMBL10407239 | 0.82 | ALOX5 (0.49) | ALOX5MEN1KMT2A | |
| SCHEMBL10407318 | 0.80 | AKR1C3 (0.41) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9829355 | 0.78 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL9833165 | 0.78 | CHRM2 (0.48) | ALOX5KMT2A | |
| SCHEMBL10407582 | 0.76 | ALDH1A1 (0.46) | ALOX5MAPTKCNQ2KMT2A | |
| SCHEMBL9829920 | 0.76 | MAOB (0.50) | ALOX5MAPTKCNQ2KMT2A | |
| SCHEMBL9829836 | 0.76 | MAOB (0.36) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL17893759 | 0.76 | MAOB (0.36) | ALOX5MAPTKCNQ2KMT2A | |
| SCHEMBL9830246 | 0.74 | HSP90AA1 (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | claimed |