Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14336886 | 0.88 | MAOB (0.45) | MAOBALOX5ALDH1A1KMT2AADAMTS5 | |
| SCHEMBL9831491 | 0.82 | ALDH1A1 (0.37) | MAOBALDH1A1KMT2AKCNQ2 | |
| SCHEMBL10408119 | 0.82 | ALOX5 (0.49) | MAOBALOX5ALDH1A1KMT2AMAPT | |
| SCHEMBL568685 | 0.80 | MAOB (0.49) | MAOBALDH1A1MAPT | |
| SCHEMBL9831309 | 0.78 | ALDH1A1 (0.37) | MAOBALDH1A1KMT2A | |
| SCHEMBL9833165 | 0.78 | CHRM2 (0.48) | ALOX5KMT2AADAMTS5 | |
| SCHEMBL10407582 | 0.76 | ALDH1A1 (0.46) | ALOX5ALDH1A1KMT2AMAPTKCNQ2 | |
| SCHEMBL9831474 | 0.76 | ALOX5 (0.33) | ALOX5KMT2AMAPTKCNQ2 | |
| SCHEMBL1410628 | 0.76 | ADRB1 (0.51) | ALOX5ALDH1A1KMT2AMAPT | |
| SCHEMBL10408425 | 0.76 | RAD51 (0.40) | MAOBALDH1A1KMT2AADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | claimed |
| US-4925939-A | 6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-05-15 | — | — | US | disclosed |