Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 9/20 | 0.47 |
| ▸ | FNTB | P49356 | 9/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831936 | 1.00 | TAS1R3 (0.56) | TAS1R3TAS1R1MEN1KMT2ACTSL | |
| SCHEMBL4955422 | 0.87 | ALDH1A1 (0.53) | MEN1KMT2AFNTAFNTBUSP2 | |
| SCHEMBL9830017 | 0.87 | ALDH1A1 (0.53) | MEN1KMT2AFNTAFNTBUSP2 | |
| SCHEMBL10660362 | 0.85 | TAS1R3 (0.72) | TAS1R3TAS1R1MEN1KMT2ACTSL | |
| SCHEMBL10660357 | 0.85 | TAS1R3 (0.72) | TAS1R3TAS1R1MEN1KMT2ACTSL | |
| SCHEMBL9831590 | 0.84 | CA2 (0.53) | MEN1KMT2ASMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL9831597 | 0.84 | CA2 (0.53) | MEN1KMT2ASMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL9829708 | 0.83 | CA2 (0.48) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL9829699 | 0.83 | CA2 (0.48) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL9831838 | 0.80 | TAS1R3 (0.58) | TAS1R3TAS1R1MEN1KMT2ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |