Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 6/20 | 0.44 |
| ▸ | FNTB | P49356 | 6/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829699 | 1.00 | CA2 (0.48) | CA2CA1CA12CA9FNTA | |
| SCHEMBL9831504 | 0.87 | CA2 (0.51) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL9831508 | 0.87 | CA2 (0.51) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL9831936 | 0.83 | TAS1R3 (0.56) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL9831941 | 0.83 | TAS1R3 (0.56) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL4955422 | 0.83 | ALDH1A1 (0.53) | CA2CA1CA12CA9FNTA | |
| SCHEMBL9830017 | 0.83 | ALDH1A1 (0.53) | CA2CA1CA12CA9FNTA | |
| SCHEMBL9830491 | 0.80 | CA2 (0.60) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL9830488 | 0.80 | CA2 (0.60) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL10654618 | 0.77 | PPARG (0.50) | CA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |