Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 13/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867071 | 0.68 | KDR (0.35) | ABL1KDRXDH | |
| SCHEMBL9121031 | 0.68 | MAP2K1 (0.37) | MAP2K1MAPK8DYRK1ACLK4DYRK1B | |
| SCHEMBL11939795 | 0.68 | TDP1 (0.34) | MAP2K1MAPK8DYRK1ACLK4DYRK1B | |
| SCHEMBL18358350 | 0.65 | CHEK1 (0.39) | EGLN2MAP2K1MAPK8DYRK1ACLK4 | |
| SCHEMBL17873877 | 0.65 | HAVCR2 (0.41) | EGLN2MAP2K1MAPK8DYRK1ACLK4 | |
| SCHEMBL11883707 | 0.65 | NUDT1 (0.41) | EGLN2MAP2K1DYRK1ACLK4CHEK1 | |
| SCHEMBL557383 | 0.64 | MAP2K1 (0.44) | MAP2K1DYRK1ADYRK1BCHEK1MAP4K4 | |
| SCHEMBL3132349 | 0.62 | USP2 (0.38) | MAP2K1 | |
| SCHEMBL25664506 | 0.62 | MAPK8 (0.35) | MAPK8DYRK1ACLK4DYRK1B | |
| SCHEMBL12335785 | 0.58 | MAP2K1 (0.53) | MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489238-B1 | PHARMACEUTICAL COMPOSITIONS OF 6H-PYRIDO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-ONE AND [1,2,4]TRIAZOLO[1,5-C]PTERIDIN-5(6H)-ONE DERIVATIVES AS PDE1 INHIBITORS FOR TREATING E.G. NEUROLOGICAL DISORDERS | DART NEUROSCIENCE CAYMAN LTD (KY) | 2021-10-13 | — | — | EP | claimed |
| US-12384787-B2 | Fused heterocyclic compounds and their use as pest control agents | PI INDUSTRIES LTD (IN) | 2025-08-12 | — | — | US | disclosed |
| US-12351583-B2 | Triazolopyrimidines based on thymine nucleobase and methods for producing them | CHEMITERAS, INC. (JP) | 2025-07-08 | — | — | US | disclosed |
| US-20220251094-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD. (IN) | 2022-08-11 | — | — | US | disclosed |
| US-20220194950-A1 | TRIAZOLOPYRIMIDINES BASED ON THYMINE NUCLEOBASE AND METHODS FOR PRODUCING THEM | TERA STONE CO., LTD (JP) | 2022-06-23 | — | — | US | disclosed |
| EP-3950064-A1 | THYMINE NUCLEOBASE-BASED TRIAZOLOPYRIMIDINES AND PRODUCTION METHOD THEREFOR | Tera Stone Co., Ltd (JP) | 2022-02-09 | — | — | EP | disclosed |
| EP-3489238-A1 | PHARMACEUTICAL COMPOSITIONS OF 6H-PYRIDO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-ONE AND [1,2,4]TRIAZOLO[1,5-C]PTERIDIN-5(6H)-ONE DERIVATIVES AS PDE1 INHIBITORS FOR TREATING E.G. NEUROLOGICAL DISORDERS | Dart NeuroScience (Cayman) Ltd (KY) | 2019-05-29 | — | — | EP | disclosed |
| US-8575114-B2 | SGLT-2 inhibitors, methods of making them, and uses thereof | ALBANY MOLECULAR RESEARCH, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-8575114-B2 | SGLT-2 inhibitors, methods of making them, and uses thereof | ALBANY MOLECULAR RESEARCH, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-20110237527-A1 | SGLT-2 INHIBITORS, METHODS OF MAKING THEM, AND USES THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-09-29 | — | — | US | disclosed |
| US-20110237527-A1 | SGLT-2 INHIBITORS, METHODS OF MAKING THEM, AND USES THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-09-29 | — | — | US | disclosed |
| EP-0217748-B1 | 2-Substituted-e-fused-[1,2,4,]triazolo-[1,5-c]pyrimidines pharmaceutical compositions and uses thereof | CIBA-GEIGY AG (CH) | 1991-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351583-B2 | Triazolopyrimidines based on thymine nucleobase and methods for producing them | TYMP, DPYD, DTYMK | EGLN2 3297/4885MAP2K1 1735/4885MAPK8 842/4885 |
| US-20110237527-A1 | SGLT-2 INHIBITORS, METHODS OF MAKING THEM, AND USES THEREOF | SLC5A2, SLC5A1, SLC10A1 | EGLN2 1259/4885MAP2K1 1444/4885MAPK8 2206/4885 |
| US-12384787-B2 | Fused heterocyclic compounds and their use as pest control agents | DDT, ACHE, KEAP1 | EGLN2 2772/4885MAP2K1 3755/4885MAPK8 2709/4885 |
| US-20220194950-A1 | TRIAZOLOPYRIMIDINES BASED ON THYMINE NUCLEOBASE AND METHODS FOR PRODUCING THEM | TYMP, DPYD, DTYMK | EGLN2 3297/4885MAP2K1 1735/4885MAPK8 842/4885 |
| US-20220251094-A1 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | DDT, ACHE, KEAP1 | EGLN2 2772/4885MAP2K1 3755/4885MAPK8 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.