Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830333 | 0.90 | KMT2A (0.37) | ALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL9833863 | 0.90 | ACLY (0.46) | ACLYALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL9833369 | 0.89 | SLC40A1 (0.36) | GAASMN1; SMN2GRM5 | |
| SCHEMBL9834094 | 0.89 | ACLY (0.39) | ACLYALDH1A1HSD17B10DHODH | |
| SCHEMBL9832083 | 0.88 | ACLY (0.39) | ACLYDHODHMETAP2 | |
| SCHEMBL9831623 | 0.88 | TSHR (0.43) | ALDH1A1KDM4ENPC1TP53GAA | |
| SCHEMBL9833225 | 0.87 | MEN1 (0.38) | ACLYALDH1A1GAADHODHKAT6A | |
| SCHEMBL9833287 | 0.87 | LMNA (0.32) | NPC1 | |
| SCHEMBL9831402 | 0.86 | TSHR (0.36) | GRM5 | |
| SCHEMBL8356736 | 0.84 | SLC40A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |