Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832148 | 0.90 | FFAR4 (0.37) | ACLYPOLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9832072 | 0.90 | ACLY (0.35) | ACLYMETAP2POLBKDM4EALDH1A1 | |
| SCHEMBL9832083 | 0.90 | ACLY (0.39) | ACLYMETAP2HPGDLMNAMEN1 | |
| SCHEMBL9833246 | 0.90 | ACLY (0.52) | ACLYMETAP2POLBKDM4ELMNA | |
| SCHEMBL9833898 | 0.87 | METAP2 (0.33) | ACLYMETAP2KDM4EALDH1A1HPGD | |
| SCHEMBL9831601 | 0.87 | LMNA (0.39) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9833225 | 0.87 | MEN1 (0.38) | ACLYALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9834365 | 0.86 | METAP2 (0.33) | ACLYMETAP2KDM4EALDH1A1PDE2A | |
| SCHEMBL9831620 | 0.86 | NPC1 (0.33) | ACLYPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL9831767 | 0.85 | SLC40A1 (0.31) | METAP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |