Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521089 | 0.70 | ALOX5 (0.38) | ALDH1A1KMT2AHSD17B10POLBMEN1 | |
| SCHEMBL30475628 | 0.69 | KDM4E (0.42) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL1472784 | 0.68 | MAPK1 (0.53) | ALDH1A1HSD17B10POLBMAPTHPGD | |
| SCHEMBL9200910 | 0.66 | — | — | |
| SCHEMBL9833266 | 0.65 | HSD11B1 (0.59) | POLBHSD17B2ALOX5L3MBTL1 | |
| SCHEMBL467448 | 0.64 | — | — | |
| SCHEMBL4523411 | 0.63 | CYP2D6 (0.50) | ALDH1A1KMT2AHPGDMAPK1 | |
| SCHEMBL3285780 | 0.63 | CYP2D6 (0.50) | ALDH1A1KMT2AHPGDMAPK1 | |
| SCHEMBL2132365 | 0.63 | CYP2D6 (0.50) | ALDH1A1KMT2AHPGDMAPK1 | |
| SCHEMBL9489951 | 0.63 | KDM4E (0.37) | ALDH1A1KMT2AHSD17B10POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209352-B1 | PROCESS AND INTERMEDIATES FOR BETA-LACTAM ANTIBIOTICS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-05-02 | — | — | EP | disclosed |