Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830216 | 0.95 | MAPT (0.44) | NAAAHTR2CHCAR2NOD1MAPT | |
| SCHEMBL2123199 | 0.95 | ALDH1A1 (0.44) | HCAR2NOD1MAPTTSHRALDH1A1 | |
| SCHEMBL9184074 | 0.93 | MAPT (0.47) | NAAAHTR2CHCAR2NOD1MAPT | |
| SCHEMBL9362410 | 0.93 | MAPT (0.47) | NAAAHTR2CHCAR2NOD1MAPT | |
| SCHEMBL7996533 | 0.90 | GSR (0.44) | HCAR2MAPTGPR84FFAR1ALDH1A1 | |
| SCHEMBL251336 | 0.89 | NAAA (0.48) | NAAAHCAR2NOD1MAPTEPHX1 | |
| SCHEMBL7449124 | 0.88 | MAPT (0.44) | MAPTGPR84FFAR1ALDH1A1CPB2 | |
| SCHEMBL4949251 | 0.87 | MAPT (0.55) | NAAAHCAR2NOD1MAPTEPHX1 | |
| SCHEMBL10523806 | 0.87 | MAPT (0.55) | NAAAHCAR2NOD1MAPTEPHX1 | |
| SCHEMBL9363102 | 0.86 | NAAA (0.47) | NAAAHTR2CEPHX1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |