SCHEMBL7996533

SCHEMBL7996533

CCCCOC(=O)C(CCCCN)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.44
RNPEP Q9H4A4 1/20 0.43
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
CPB2 Q96IY4 4/20 0.41
ATM Q13315 1/20 0.40
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
GPR84 Q9NQS5 3/20 0.39
FFAR1 O14842 1/20 0.39
SLC6A5 Q9Y345 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7449124 0.98 MAPT (0.44) GSRRNPEPALDH1A1MAPTCPB2
SCHEMBL9830216 0.95 MAPT (0.44) GSRRNPEPMAPTCPB2GNAI3
SCHEMBL2123199 0.95 ALDH1A1 (0.44) GSRALDH1A1MAPTCPB2ATM
SCHEMBL9184074 0.93 MAPT (0.47) MAPTCPB2GNAI3GNAO1GNAI1
SCHEMBL9362410 0.93 MAPT (0.47) MAPTCPB2GNAI3GNAO1GNAI1
SCHEMBL9832203 0.90 NAAA (0.43) ALDH1A1MAPTCPB2HCAR2GPR84
SCHEMBL9830707 0.90 CPB2 (0.45) GSRRNPEPMAPTCPB2GNAI3
SCHEMBL5983037 0.89 ALDH1A1 (0.45) ALDH1A1MAPTATMHCAR2
SCHEMBL28070253 0.87 MAPT (0.55) ALDH1A1MAPTATMHCAR2GPR84
SCHEMBL7633731 0.87 ALDH1A1 (0.50) ALDH1A1MAPTATMHCAR2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0773950-A4 LINKED PEPTIDE NUCLEIC ACIDS ISIS PHARMACEUTICALS INC (US) 2000-05-17 EP disclosed
EP-0804456-A4 PEPTIDE NUCLEIC ACID CONJUGATES ISIS PHARMACEUTICALS INC (US) 1999-05-19 EP disclosed
EP-0804456-A1 PEPTIDE NUCLEIC ACID CONJUGATES ISIS PHARMACEUTICALS, INC. (US) 1997-11-05 EP disclosed
EP-0773950-A1 LINKED PEPTIDE NUCLEIC ACIDS ISIS PHARMACEUTICALS, INC. (US) 1997-05-21 EP disclosed
WO-1996011205-A9 PEPTIDE NUCLEIC ACID CONJUGATES 1996-05-30 WO disclosed
WO-1996011205-A1 PEPTIDE NUCLEIC ACID CONJUGATES ISIS PHARMACEUTICALS, INC. (US) 1996-04-18 WO disclosed
WO-1996002558-A1 LINKED PEPTIDE NUCLEIC ACIDS ISIS PHARMACEUTICALS, INC. (US) 1996-02-01 WO disclosed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed