Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829551 | 0.86 | PTPN1 (0.35) | ADAMTS5MAPTPOLBALDH1A1TSHR | |
| SCHEMBL9830732 | 0.84 | ADAMTS5 (0.36) | ADAMTS5MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL9831349 | 0.84 | ADAMTS5 (0.34) | ADAMTS5MAPTPOLBALDH1A1TSHR | |
| SCHEMBL9828736 | 0.78 | MEN1 (0.44) | ADAMTS5MAPTCYP2C19ALDH1A1TSHR | |
| SCHEMBL9829147 | 0.78 | SMPD1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL9832211 | 0.77 | SMPD1 (0.50) | ALOX15 | |
| Hydrochloric Acid SCHEMBL9829963 | 0.77 | SMPD1 (0.34) | MAPTCYP2C19ALDH1A1TSHRRAB9A | |
| SCHEMBL9828526 | 0.76 | SMPD1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL9831196 | 0.76 | SMPD1 (0.49) | ALOX15 | |
| Hydrochloric Acid SCHEMBL9831706 | 0.76 | BCHE (0.35) | MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |