Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 14/20 | 0.42 |
| ▸ | HRH1 | P35367 | 14/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830856 | 0.82 | TMEM97 (0.50) | HRH3MAOB | |
| SCHEMBL9830032 | 0.81 | CACNA1B (0.43) | HRH3HRH2HRH1 | |
| SCHEMBL9830080 | 0.80 | ALDH1A1 (0.42) | HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL9829638 | 0.78 | ALDH1A1 (0.41) | HRH2HRH1 | |
| SCHEMBL9831388 | 0.77 | ALDH1A1 (0.37) | HRH3 | |
| Hydrochloric Acid SCHEMBL10674867 | 0.76 | HRH3 (0.45) | HRH3MAOBHRH2HRH1 | |
| Hydrochloric Acid SCHEMBL9829279 | 0.75 | LSS (0.37) | — | |
| Hydrochloric Acid SCHEMBL9828036 | 0.74 | KCNH2 (0.45) | HRH3MAOBHRH2HRH1 | |
| Oxalic Acid SCHEMBL10669220 | 0.74 | KDM4E (0.48) | HRH2 | |
| SCHEMBL9829983 | 0.72 | CYP1A2 (0.40) | HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |