Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.50 |
| ▸ | WNT3A | P56704 | 3/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15974682 | 0.84 | ERCC5 (0.57) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL471019 | 0.81 | ALDH1A1 (0.69) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| Hydrochloric Acid SCHEMBL3303 | 0.80 | ALDH1A1 (0.67) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL31419978 | 0.79 | TSHR (0.59) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL13044823 | 0.78 | LMNA (0.69) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL11316585 | 0.78 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL1923026 | 0.78 | ERCC5 (0.59) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL1232758 | 0.78 | — | — | |
| SCHEMBL14139292 | 0.78 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL287873 | 0.78 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1021051-C | THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING SAME | TANABE SEIYAKU CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4857543-A | TREATMENT OF GASTROINTESTINAL DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| CN-1030584-A | Novel thiophene derivant and preparation method thereof | TANABE SEIYAKU CO (JP) | 1989-01-25 | — | — | CN | disclosed |
| EP-0297782-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |