Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832426 | 0.76 | ALOX5 (0.71) | ALOX5KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9730349 | 0.71 | ALOX5 (0.55) | ALOX5KMT2AGSRSMN1; SMN2 | |
| SCHEMBL3192132 | 0.69 | MCHR1 (0.52) | ALOX5ALDH1A1TSHR | |
| Tetrabuthylammonium SCHEMBL9833807 | 0.66 | ALOX5 (0.55) | ALOX5KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9831966 | 0.66 | MAPT (0.48) | ALOX5KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL11657126 | 0.65 | GSR (0.56) | KMT2AMEN1ALDH1A1GSRSMN1; SMN2 | |
| SCHEMBL12220052 | 0.65 | L3MBTL1 (0.68) | KMT2AMEN1ALDH1A1GSRSMN1; SMN2 | |
| SCHEMBL6992415 | 0.65 | MEN1 (0.47) | ALOX5KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9832106 | 0.64 | ALOX5 (0.53) | ALOX5KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9542469 | 0.64 | ALOX5 (0.60) | ALOX5KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388429-A4 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | — | 1991-08-21 | — | — | EP | disclosed |
| EP-0388429-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-09-26 | — | — | EP | disclosed |
| WO-1989004299-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-05-18 | — | — | WO | disclosed |