Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | GSR | P00390 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807791 | 0.71 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9832797 | 0.71 | ALOX5 (0.43) | ALOX5GSRSMN1; SMN2KMT2A | |
| Ammonia Solution, Strong SCHEMBL8807165 | 0.70 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL8806921 | 0.70 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL8806331 | 0.69 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL11657126 | 0.67 | GSR (0.56) | GSRSMN1; SMN2KMT2APTGS2AKR1C3 | |
| SCHEMBL3285163 | 0.66 | HPGD (0.43) | ALOX5SMN1; SMN2 | |
| SCHEMBL8808277 | 0.64 | ALOX5 (0.57) | ALOX5SMN1; SMN2KMT2A | |
| SCHEMBL8049079 | 0.64 | ENPP2 (0.50) | GSRPTGS2AKR1C3 | |
| SCHEMBL12220052 | 0.63 | L3MBTL1 (0.68) | GSRSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112848-A | Antiasthmatics and antiarthritic agents | ABBOTT LABORATORIES (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0320628-A1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LABORATORIES (US) | 1989-06-21 | — | — | EP | disclosed |