Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | ME2 | P23368 | 1/20 | 0.44 |
| ▸ | ME1 | P48163 | 1/20 | 0.44 |
| ▸ | ME3 | Q16798 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5892112 | 0.85 | GSTP1 (0.59) | NPC1RAB9AGSTP1 | |
| SCHEMBL21852751 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KDM4ELMNATDP1NPSR1 | |
| SCHEMBL5892137 | 0.78 | ADORA2A (0.51) | ALDH1A1NPSR1HPGDKMT2AMEN1 | |
| SCHEMBL5892101 | 0.77 | L3MBTL1 (0.46) | ALDH1A1KDM4ELMNATDP1NPSR1 | |
| SCHEMBL14525866 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNATDP1NPSR1 | |
| SCHEMBL16266535 | 0.76 | L3MBTL1 (0.53) | ALDH1A1KDM4ELMNATDP1L3MBTL1 | |
| SCHEMBL10444906 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNATDP1NPSR1 | |
| SCHEMBL115647 | 0.74 | LMNA (0.47) | ALDH1A1KDM4ELMNANPSR1L3MBTL1 | |
| SCHEMBL10508211 | 0.72 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNATDP1NPSR1 | |
| SCHEMBL5892120 | 0.72 | KIF11 (0.45) | ALDH1A1KDM4ELMNAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239972-B1 | 3, 3'(2H,2'H)-SPIROBIBENZOFURAN COMPOUNDS AND ANTIOXIDANTS COMPRISING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-18 | — | — | EP | claimed |
| US-4864039-A | OXIDATION RESISTANCE FOR DYES, RUBBERS, PLASTICS, PETROLEUM; COLORFASTNESS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-09-05 | — | — | US | claimed |
| EP-0187620-B1 | DITHIOKETO-PYRROLO-PYRROLES, PROCESS FOR THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1991-04-17 | — | — | EP | disclosed |
| US-4868101-A | SPIROBIBENZOFURANS AS DYE STABILIZERS DISCOLORATION INHIBITIONS; COLOR PRESERVATION | FUJI PHOTO FILM CO., LTD. (JP) | 1989-09-19 | — | — | US | disclosed |
| US-4760151-A | Dithioketo pyrrolopyrroles | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| US-4632893-A | CHARGE GENERATING AND TRANSPORTING LAYERS; DARK RESISTANCE; POLYMERIC DYES | CIBA-GEIGY CORPORATION (US) | 1986-12-30 | — | — | US | disclosed |
| EP-0187620-A2 | Dithioketo-pyrrolo-pyrroles, process for their preparation and use | CIBA-GEIGY AG (CH) | 1986-07-16 | — | — | EP | disclosed |