Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832418 | 0.90 | ACLY (0.40) | ACLYELANEMEN1LMNAKMT2A | |
| SCHEMBL9833863 | 0.90 | ACLY (0.46) | ACLYPOLBMETAP2KDM4EMEN1 | |
| SCHEMBL9834094 | 0.89 | ACLY (0.39) | ACLYCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9831777 | 0.87 | SLC40A1 (0.37) | ACLYGFERCCR4KMT2A | |
| SCHEMBL9832083 | 0.86 | ACLY (0.39) | ACLYMETAP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9832654 | 0.82 | CCR4 (0.34) | CCR4KMT2A | |
| SCHEMBL9832065 | 0.81 | MAPT (0.36) | CCR2KDM4EMEN1LMNAKMT2A | |
| SCHEMBL9833251 | 0.80 | ELANE (0.36) | ACLYELANENPC1ALOX15HTT | |
| SCHEMBL8358795 | 0.80 | SLC40A1 (0.36) | GFERKMT2A | |
| SCHEMBL9832072 | 0.80 | ACLY (0.35) | ACLYPOLBMETAP2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |