Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.38 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833352 | 0.84 | TDP1 (0.41) | TDP1PLCG2PCTPRAB9APOLB | |
| SCHEMBL9834942 | 0.84 | NPC1 (0.39) | RAB9ANPC1PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL9834688 | 0.83 | TRPM8 (0.37) | TDP1RAB9ANPC1PKMLMNA | |
| SCHEMBL9832964 | 0.78 | TDP1 (0.47) | TDP1PLCG2PCTPRAB9APOLB | |
| SCHEMBL10672708 | 0.78 | ALDH1A1 (0.50) | TDP1PCTPRAB9APOLBNPC1 | |
| SCHEMBL10773468 | 0.78 | TDP1 (0.51) | TDP1PLCG2PCTPRAB9APOLB | |
| SCHEMBL10666650 | 0.76 | ALDH1A1 (0.53) | TDP1PCTPRAB9APOLBNPC1 | |
| SCHEMBL9834614 | 0.76 | MEN1 (0.38) | TDP1RAB9ANPC1PKMMAPT | |
| SCHEMBL9835209 | 0.75 | TDP1 (0.41) | TDP1PLCG2PCTPRAB9APOLB | |
| SCHEMBL10798551 | 0.74 | PYGL (0.48) | TDP1PLCG2PCTPRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211665-B1 | BENZOYL-UREAS HAVING ACARICIDE AND INSECTICIDE ACTIVITY | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1991-06-12 | — | — | EP | claimed |
| EP-0211665-A2 | Benzoyl-ureas having acaricide and insecticide activity | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1987-02-25 | — | — | EP | claimed |